1H-Pyrrolo[2,3-b]pyridine, 4-methyl-5-(trifluoromethyl)-
4-Methyl-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine
CAS: 1261365-79-0
Molecular Formula: C9H7F3N2
1H-Pyrrolo[2,3-b]pyridine, 4-methyl-5-(trifluoromethyl)- - Names and Identifiers
| Name | 4-Methyl-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine |
| Synonyms | 4-Methyl-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine 1H-Pyrrolo[2,3-b]pyridine, 4-methyl-5-(trifluoromethyl)- |
| CAS | 1261365-79-0 |
1H-Pyrrolo[2,3-b]pyridine, 4-methyl-5-(trifluoromethyl)- - Physico-chemical Properties
| Molecular Formula | C9H7F3N2 |
| Molar Mass | 200.16 |
| Storage Condition | 2-8℃ |
| Sensitive | IRRITANT |
| MDL | MFCD18374147 |
1H-Pyrrolo[2,3-b]pyridine, 4-methyl-5-(trifluoromethyl)- - Risk and Safety
| Hazard Symbols | T - Toxic |
| Risk Codes | 25 - Toxic if swallowed |
| Safety Description | 45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| Hazard Class | IRRITANT |
1H-Pyrrolo[2,3-b]pyridine, 4-methyl-5-(trifluoromethyl)- - Introduction
4-Methyl-5-(trifluoromethyl)-1H-cryrolo [2,3-b]pyridine is an organic compound with the chemical formula C10H7F3N2. It is a solid with a white to pale yellow appearance.
Its main use is as an intermediate in organic synthesis. It is often used as an important intermediate of drugs and pesticides, such as anti-cancer drugs, antiviral drugs and antibacterial drugs in drug development. In addition, it can also be used as a synthetic raw material in the fields of dyes and coatings.
The method of preparing 4-Methyl-5-(trifluoromethyl)-1H-cryrolo [2,3-b]pyridine can take many routes. A common method is to generate the corresponding acylcyano compound by the reaction of cyanide and acid chloride, then introduce the trifluoromethyl group by fluorination reaction, and finally obtain the target product by ring-closing reaction.
Regarding safety information, the 4-Methyl-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine must be handled with care. It can be irritating to the eyes, skin, and respiratory system, so wear appropriate personal protective equipment such as laboratory gloves, safety glasses, and work clothes during handling or contact. In addition, the operation should be carried out in a well-ventilated place to avoid inhalation of gas or solution. In case of misuse or inadvertent contact, seek immediate medical attention or professional first aid.
Its main use is as an intermediate in organic synthesis. It is often used as an important intermediate of drugs and pesticides, such as anti-cancer drugs, antiviral drugs and antibacterial drugs in drug development. In addition, it can also be used as a synthetic raw material in the fields of dyes and coatings.
The method of preparing 4-Methyl-5-(trifluoromethyl)-1H-cryrolo [2,3-b]pyridine can take many routes. A common method is to generate the corresponding acylcyano compound by the reaction of cyanide and acid chloride, then introduce the trifluoromethyl group by fluorination reaction, and finally obtain the target product by ring-closing reaction.
Regarding safety information, the 4-Methyl-5-(trifluoromethyl)-1H-pyrrolo[2,3-b]pyridine must be handled with care. It can be irritating to the eyes, skin, and respiratory system, so wear appropriate personal protective equipment such as laboratory gloves, safety glasses, and work clothes during handling or contact. In addition, the operation should be carried out in a well-ventilated place to avoid inhalation of gas or solution. In case of misuse or inadvertent contact, seek immediate medical attention or professional first aid.
Last Update：2024-04-09 20:52:54
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